The 34-year-old Cave, who won the Ironman 70.3 world championship in Las Vegas last month and the Ironman world championship in Hawaii two weeks ago, has confirmed her participation in the third Ironman 70.3 Laguna Phuket.
"She has signed up for our Ironman 70.3 just hours after becoming the world champion in Las Vegas," said Debbie Dionysius, Laguna Phuket's assistant vice president of destination marketing.
Cave is expected to face a tough challenge from Phuket defending champion Melissa Hauschildt of Australia who was fourth at this year's world championship in Las Vegas.
Meanwhile, the 19th Laguna Phuket Triathlon will take place on Nov 25.
Australia's Belinda Granger and Czech Radka Vodickova are vying to become the event's first-ever women's triple champion.
Italian Massimo Cigana, the tournament's first-ever triple champion, will return to defend his title in a bid to be a four-time champion. He will face stiff opposition from elite pros such as Chris Lieto.